Karitas is the Co-Founder and CEO of Sygnia Media Productions, a media and content-creation company; a Co-Founder Director at Imbuto Zera Africa, a social enterprise dedicated to youth involvement and empowerment in environmental and agriculture causes; Founder of KariKari, a wellness and beauty company; and Karitas Karisimbi Foundation, a not-for-profit organisation dedicated to building a better future for the Boy Child in Uganda.